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This article mainly introduces the use of the ANFD-HLA database, has a certain reference value, interested friends can refer to, I hope you can learn a lot after reading this article, the following let the editor take you to understand it.

In the study of SNP, we have databases such as 1000G HapMap and Exac, which provide frequency information in different populations. For the research of HLA, there is also a database for storing frequency information-ANFD.

The link to the official website is as follows

Http://www.allelefrequencies.net/default.asp

ANFD, whose full name is Allel Frequency Net Database, stores highly polymorphic mutation information in four human genomes, including HLA, KIR,Cytokine and MIC, in which allel, haplotype and genotype are recorded. The most important thing is that it provides frequency information in different populations.

1. The frequency of Allel in different populations.

Through the retrieval function of the database, you can query the frequency distribution of HLA Allel in different populations.

Http://www.allelefrequencies.net/hla6006a.asp

Locus specifies the HLA locus, Population specifies the population, and then click the Search button. The search results of the above conditions are as follows

2. The frequency of haplotype in different populations

Due to the close linkage of HLA gene clusters, in addition to the frequency of a single Allel, the frequency of related haplotypes also needs to be concerned. The official website also provides the function of searching haplotypes, and the URL is as follows

Http://www.allelefrequencies.net/hla6003a.asp

By selecting the gene combinations that constitute haplotypes, and then searching them. The retrieval results of the above conditions are as follows

Through the ANFD database, we can easily get the frequency information of HLA Allel and haplotype in the crowd. In addition, the official website also provides many other functions that need to be further studied and used.

Thank you for reading this article carefully. I hope the article "what's the use of ANFD-HLA database" shared by the editor will be helpful to you? at the same time, I also hope you will support us and pay attention to the industry information channel. More related knowledge is waiting for you to learn!

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