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Editor to share with you what is the use of EnhancerAtlas database, I believe most people do not know much about it, so share this article for your reference, I hope you can learn a lot after reading this article, let's go to know it!

EnhancerAtlas combines the analysis results of three high-throughput data to predict enhancers in humans and mice. The latest version of the database is v2.0, available at

Http://www.enhanceratlas.org/index2.php

For human enhancers, the prediction based on the hg19 genome version currently contains 4506217 enhancers from 170 cells or tissues, while for mouse enhancers, based on the mm9 genome version, there are 2811699 enhancers from 150 cells or tissues.

Support direct input of gene names or specific regions of the genome to view enhancers in that region, as shown below

The search results are as follows

The display form of the genome browser is adopted, and each line is called track. The black font corresponding line represents the reads coverage result of this region detected by each method, and the red font corresponding behavior synthesizes the enhanced sub-region results obtained by various methods.

On the results page, you can download the fasta sequence file of enhancers contained in this area, as shown below

The expression of enhancers in different cell lines can also be compared. The search box is shown below.

The search results are as follows

The expression of enhancers in different cell lines can be compared intuitively. The database also supports the display of regulatory networks between enhancers and genes. The search box is shown below.

The results of the regulatory network are as follows

In addition to the online retrieval function, the data in the database can also be downloaded free of charge, whether it is the enhancer sub-interval in different cell lines or the regulatory network between enhancers and genes. For enhancer research, the database is very worthy of reference.

The above is all the contents of the article "what is the use of EnhancerAtlas database". Thank you for reading! I believe we all have a certain understanding, hope to share the content to help you, if you want to learn more knowledge, welcome to follow the industry information channel!

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