Shulou(Shulou.com)12/24 Report--

CTOnews.com, December 1 (Xinhua)-- regular blood sugar tests are essential for people with diabetes, and each test requires pricking fingers. Scientists from Canada and the United States have now developed a prototype household device that can measure blood sugar levels through saliva samples.

Tuyuan personaltouchfitness currently has an industry consensus that the concentration of glucose (and some other biomarker chemicals) in human saliva is proportional to the concentration in its blood.

However, because the levels of glucose in saliva are much lower, special laboratory equipment is needed to measure them accurately.

Researchers from the University of Sherbrook Quebec and Colgate Palmolive in New Jersey have developed biosensors based on electrochemical aptamers (E-AB).

The device contains a specially designed DNA fragment (called aptamer) that binds to target biomarkers in the sample and the sensor produces measurable electrochemical signals.

Aptamers used in E-AB biosensors are usually not sensitive enough to reliably detect glucose in saliva.

Philippe Dauphin-Ducharme, an assistant professor at the University of Sherbrook in Quebec, and his colleagues have improved the sensitivity of aptamers, which have been shown to successfully measure glucose levels in the blood.

The sensor not only accurately measures the concentration of glucose in saliva (it takes only 30 seconds to provide a reading), but also maintains sensitivity for up to a week as long as it is washed and stored in phosphate buffered saline solution after each use.

CTOnews.com attached the reference address of the paper: Electrochemical Aptamer-Based Biosensors for Measurements in Undiluted Human SalivaMinh-Dat Nguyen, Khoa-Nam Nguyen, Samuel Malo, Indrani Banerjee, Donghui Wu, Laurence Du-Thumm, and Philippe Dauphin-DucharmeACS Sensors Article ASAPDOI: 10.1021/acssensors.3c01624

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