Shulou(Shulou.com)11/24 Report--

With the introduction of the third generation gene sequencing technology, the research field of bioinformatics has been widely expanded, which not only provides more possibilities for deep mining of gene information, but also brings massive data analysis and processing tasks.

Beijing Hope Group Biotechnology Co., Ltd. (hereinafter referred to as Hope Group), when creating a new third-generation sequencing project delivery platform, cited the volcano engine Bio-OS solution to establish a web-based Shengxin data analysis platform, which not only effectively reduced the threshold for Shengxin data analysis, but also reduced after-sales labor costs by 40%, and operation and maintenance costs by 30%.

Hope Group (Grandomics) is a world-renowned third-generation sequencing technology developer and the first third-generation sequencing service company in China. Over the years, it has been focusing on technology development and application expansion on the third-generation sequencing platform, and has independently developed a number of third-generation sequencing software and technologies, such as genome variation analysis system and single-cell sequencing technology. and built a third-generation sequencing high-performance computing cluster to provide customers with high-quality third-generation sequencing analysis and storage services.

Photo Source: Grandomics official website

The third generation sequencing is developing rapidly, and the underlying scheduling is facing challenges.

In recent years, the third generation sequencing technology has developed rapidly, which provides high-resolution data for genome research. Hope Group is committed to creating a third-generation sequencing project delivery platform to help users analyze Shengxin data through a visual interface to reduce difficulty and improve efficiency. However, the analysis process of Shengxin data is complex, and the calculation tasks are numerous and fluctuating, so it is necessary to deal with massive unstructured file data. Therefore, through the management scheduling capability of heterogeneous clusters, we hope to achieve resource reuse, reduce costs and improve the convenience of cluster expansion.

Volcano engine Bio-OS, help Shengxin data analysis

Shengxin data analysis platform

With the support of volcano engine Bio-OS solution, Hope Group successfully built a Shengxin data analysis platform based on web. This platform can not only make full use of the existing local computing resources for health letter computing, but also facilitate its customers to submit their own analysis process through the web page to obtain the analysis results. The platform has the characteristics of seamless integration of elastic containers, fast start-up of a large number of instances, and flexibility to cope with computing peaks. In addition, the introduction of these features also effectively reduces the labor cost of after-sales support.

The three advantages of Shengxin data analysis platform:

Reduce cost and increase efficiency, resource utilization: it is hoped that the group will introduce Bio-OS solution to convert old computing resources into valuable resources by bringing local SGE clusters into the management scope of private clusters, so as to further improve computing efficiency, reduce resource waste and reduce maintenance costs.

Process simplification and operational traceability: by presetting a series of analysis steps in the workflow, Bio-OS hopes that the group will successfully lower the threshold for bioinformatics data analysis. Non-professionals such as experimenters and doctors can also easily start complex data analysis processes without in-depth understanding of technical details. At the same time, different versions of the workflow are managed by git to ensure the traceability and retrospective of the operation.

Container cluster, intelligent management: in the aspect of computing resource management, the Bio-OS scheme of volcano engine introduces elastic container, which enables the system to start and stop computing instances quickly to adapt to the changes of computing tasks. Especially when dealing with the computing peak, it can still ensure that the system runs efficiently and will not fall into delay due to the increase of load.

The after-sales cost is reduced by 40% and the operation and maintenance cost is reduced by 30%.

Shengxin data analysis platform effectively reduces the threshold of Shengxin data analysis, so that ordinary people can easily start the journey of data analysis. In addition, Bio-OS manages the local SGE cluster to make full use of local computing power, which not only improves the efficiency of cluster management, but also reduces 40% after-sales support manpower cost and 30% operation and maintenance cost.

At present, Hope Group has also developed tools such as petal map, dynamic volcano map, single-cell gene expression reduced-dimension map, single-cell reduced-dimensional cluster map and so on on the basis of notebook tools integrated by Bio-OS platform. With the continuous evolution of technology, the combination of gene sequencing and Bio-OS will expand our understanding of the meaning and application of the genome, and create more development opportunities.

END

A few days ago, six companies in the field of Shengxin, including Volcano engine and Genome Society, jointly released the "2023 Blue Book of the Genome Industry." In the future, the volcanic engine will continue to provide support for scientific and technological research and development, and inject more impetus into the innovation and development in the field of bioinformatics.

For more details, please click to read the original article and download the 2023 Blue Book of the genetic Industry.

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