Shulou(Shulou.com)11/24 Report--

CTOnews.com, August 24 (Xinhua)-- two genetic papers have been published in the international academic journal Nature. Researchers have assembled and analyzed the human Y chromosome, becoming the final human chromosome to be fully sequenced.

This study, which is participated by more than 100 scientists around the world, fills many gaps in the current reference of Y chromosome, which can not only provide references and insights into population evolution and variation, but also can be used to treat male cancer and fertility problems.

Researchers have mapped the complete map of the human Y chromosome, revealing 62460029 DNA bases and 41 new protein-coding genes.

The paper says that human Y chromosomes have been difficult to sequence and assemble because of their complex structure. Scientists started partial sequencing as early as 2003, when only 30 million DNA bases were found.

More than half of the Y chromosomes are missing in the current human reference genome assembly, resulting in an incomplete understanding of human Y chromosomes, which limits people's understanding of its composition, complexity and differences among different populations.

The scientific team says it is still in its early stages, but using the map, it can detect mutations, connect specific features, and identify the location of genetic diseases, allowing for more targeted treatments.

CTOnews.com attaches the address of the paper here, which can be read in depth by interested users.

Referenc

Assembly of 43 human Y chromosomes reveals extensive complexity and variation

The complete sequence of a human Y chromosome

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