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This article mainly introduces the use of miRDB database, the article is very detailed, has a certain reference value, interested friends must read it!

MiRDB predicted the miRNA target gene information of many species, such as human and mouse, through the software MirTarget, and organized it into a database at the following website

Http://www.mirdb.org/

The species covered in the database are as follows

Huaman

Mouse

Rat

Dog

Chicken

The number of miRNA and target genes associated with each species is as follows

In addition to providing the target gene results predicted by the software, the database has also done a literature review. The relevant literature on the function of miRNA precursors or mature miRNA has been collected to form a miRNA functional database, called FuncMir, which contains miRNA information in both human and mouse species, as shown below.

Click the red link to view details and related pubmed literature.

The official website provides two kinds of retrieval functions.

1. Target search

Only one miRNA gene can be retrieved at a time. The search box is as follows

2. Target mining

This function is used to retrieve more than one miRNA or gene at a time. The search box is as follows

The search results are as follows

The results are sorted by TarGetScore, and since it is the result of software prediction, the higher the score value, the higher the credibility. It is generally believed that the results with score greater than 80 are relatively reliable, while those with less than 60 are less reliable.

The database provides a download function, which makes it easy to download all the information in the database, as shown below

MiRDB is essentially a miRNA target gene database predicted by software. If you only look at this database, the false positive rate of the results will be relatively high. The best way is to combine the results of multiple software predictions or databases, similar to the idea of miRWalk database, to make up for the shortcomings of a single software algorithm.

The above is all the contents of the article "what is the use of miRDB database". Thank you for reading! Hope to share the content to help you, more related knowledge, welcome to follow the industry information channel!

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