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What is the use of HPRD database

2025-01-28 Update From: SLTechnology News&Howtos shulou NAV: SLTechnology News&Howtos > Internet Technology >

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This article mainly introduces the use of HPRD database, the article is very detailed, has a certain reference value, interested friends must read it!

HPRD, whose full name is Human Protein Reference Database, is a database dedicated to storing human protein-protein interaction information. Compared with other similar databases, the protein-protein interaction information stored in this database has been verified by experiments, and has obvious advantages in quantity. The web address of the data is as follows

Http://hprd.org/index_html

In the literature, HPRD is compared with other databases, and the results are as follows

Picture A shows the data of human protein-protein interactions stored in different databases, and it can be clearly seen from the bar chart that HPRD has the largest amount of data, and there is little redundant information; picture B shows the distribution of the number of protein interactions in different databases, from which we can see that each stage is the best for HPRD.

In addition to the advantages of data quality and quantity, HPRD also provides other information about protein expression profiles, classification, domains, subcellular localization, post-transcriptional modification, pathways, and so on. The latest version of the database is release 9. The information statistics are as follows.

Through Query, you can retrieve information about a protein, as shown below

On the search results page, you can see various annotated information about the protein, as shown below

It includes molecular weight, sequence and other basic information, as well as subcellular localization, protein domain, interaction, GO annotation and other information.

Through the Browse function, you can view the protein information of a specified category, as shown below

It can be screened and viewed according to molecular category, post-transcriptional modification, subcellular localization, domain and other information.

The information in the database is downloadable, but only academically free, as shown below

For information on protein-protein interactions, Tab and XML formats are available for download.

Through this database, we can easily query the interaction network of a protein, but for the interaction network between multiple proteins, we can only deal with it from the downloaded data files.

The above is all the contents of the article "what is the use of HPRD database". Thank you for reading! Hope to share the content to help you, more related knowledge, welcome to follow the industry information channel!

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