Shulou(Shulou.com)06/01 Report--

This article mainly shows you "what is the use of TANRIC database", the content is easy to understand, clear, hope to help you solve your doubts, the following let the editor lead you to study and learn "what is the use of TANRIC database" this article.

TANRIC integrates data from TCGA, CCLE and other large tumor research projects to analyze the expression of lncRNA in a variety of tumors, and to analyze the correlation between lncRNA and clinical information, genome and other data.

The web address is as follows

Https://ibl.mdanderson.org/tanric/_design/basic/main.html

The pipeline for database construction is shown below

The analysis was based on the lncRNA in the Gencode database. Before the analysis, the lncRNA with overlap with the exon of the protein coding gene was filtered out.

Download the RNA_seq data of TCGA,CCLE and other items, quantify the lncRNA in the tumor, use the quantitative method of RPKM, and screen the lncRNA whose average expression is more than 0.3 in all samples for follow-up difference analysis.

Download the clinical information, genome and proteome data of the sample from TCGA, and analyze the correlation between lncRNA and these data, using the Spelman correlation coefficient as the threshold.

The website is divided into the following six modules

1. Summary

In this section, you can view the data source, sample number and other information of each tumor, as shown below.

Click the Show button to view the details, as shown below

2. Visualization

This section looks at the clustering results of lncRNA expression in each tumor, presented in the form of a heat map, as shown below

3. Download

This section is used to download data, as shown below

4. Analysis

The results of the other three modules are similar and are used to view the results of the lncRNA analysis, which are divided into three types of analysis as shown below

The results are shown as follows

For the study of lncRNA in tumors, this database is very worthy of reference.

The above is all the contents of the article "what is the use of TANRIC database". Thank you for reading! I believe we all have a certain understanding, hope to share the content to help you, if you want to learn more knowledge, welcome to follow the industry information channel!

Welcome to subscribe "Shulou Technology Information " to get latest news, interesting things and hot topics in the IT industry, and controls the hottest and latest Internet news, technology news and IT industry trends.