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Editor to share with you what is the use of tRNAdb database, I believe most people do not know much about it, so share this article for your reference, I hope you can learn a lot after reading this article, let's go to know it!

TRNAdb contains 12000 tRNA genes and 623 tRNA sequences from 577 species, providing not only basic sequence information, but also secondary structure data.

The link to the official website is as follows

Http://trna.bioinf.uni-leipzig.de/DataOutput/

The official website provides two ways to retrieve data, the first is the species' evolutionary tree browser, and the second is the conditional search box.

1. Evolutionary tree browser

TRNAdb provides a way to browse the evolutionary tree and click + to expand the secondary classification to find a specific species.

two。 Conditional search box

A variety of conditional retrieval methods are provided, which can be screened according to gene / sequence, according to the type of amino acid transported, or even according to the secondary structure, as shown in the following diagram.

The schematic diagram of the retrieval results is as follows

The basic information such as the species and the types of amino acids transported are given in the search results, in which the sequence information is divided into different regions of the secondary structure. The secondary structure of tRNA is in the shape of a clover, as shown below.

In tRNAdb, the secondary structure is divided into the following areas

Acc-stem

Amino acid receptive stem

D-stem

D stem

D-loop

D-ring

Ac-stem

Anti-cipher stem

Ac-loop

Anti-cipher ring

V-region

Variable arm

T-stem

T stem

T-loop

T ring

CCA

The silent end of the CCA used to connect amino acids

Click the eye icon to view a tRNA secondary structure, as shown below

At the bottom of the search results page, you can download the selected tRNA sequence

The above is all the contents of the article "what is the use of tRNAdb database". Thank you for reading! I believe we all have a certain understanding, hope to share the content to help you, if you want to learn more knowledge, welcome to follow the industry information channel!

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