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This article will explain in detail what is the use of LincSNP database for you. The editor thinks it is very practical, so I share it with you as a reference. I hope you can get something after reading this article.

LncRNA plays an important role in the occurrence and development of diseases, but what the specific role is, it needs to be explored and explored.

In the past, a large number of disease-related SNP sites have been identified by GWAS analysis. Of course, the most direct and simple analysis is to choose those SNP sites located on protein-coding genes, just as protein-coding genes account for only a small part of the total number of genes, and SNP sites on protein-coding genes account for only a small proportion of all SNP sites.

Among most of the remaining SNP sites, one class of sites has attracted the attention of scientists, which is located in the lncRNA-related SNP site. By exploring these SNP loci on lncRNA gene, it provides a new perspective for us to study the role and role of lncRNA in diseases.

LncRNA-related SNP sites include the following two types

SNP locus located in the lncRNA gene region

SNP site located in the transcription factor binding region of lncRNA gene

Whether directly on the lncRNA gene or at the transcription factor binding site that regulates the gene, the existence of the SNP site has a certain impact on the transcription of lncRNA. The strategy of SNP-lncRNA-disease is used to screen the relevant SNP sites to focus on research. Based on this idea, there are a lot of published literature, some researchers have collected and sorted out this kind of literature, and made the information into a database. It's LincSNP. The URL is as follows.

Http://210.46.80.146/lincsnp/index.html

The current version is 2.0. the disease-related lncRNA SNP loci published in the literature can be found through the Linc-confirm menu, as shown below

Through the Linc-Score function, you can search for diseases associated with specific lncRNA genes, as shown below

The database is downloaded for free

The database uses lncRNA loci as a bridge to establish the relationship between SNPs and diseases, which is worth using for reference.

This is the end of this article on "what is the use of LincSNP database". I hope the above content can be helpful to you, so that you can learn more knowledge. if you think the article is good, please share it out for more people to see.

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