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This article will explain in detail what is the use of DGVa database for you. The editor thinks it is very practical, so I share it with you as a reference. I hope you can get something after reading this article.

DGVa is a database of chromosome structure variation from EBI. Through literature review and submission by researchers, it stores the chromosome structure variation information of many species. The website is as follows.

Https://www.ebi.ac.uk/dgva

As shown in the following figure

There is a cooperative relationship between this database and NCBI's dbvar database, and the two will exchange data in time. The information of the database can be viewed through EBI's genome browser or biomart system, and it also provides FTP download function. In addition, some of the information in the database is also imported into the DGV database.

Consistent with the dbvar database, the information in the database is divided into the following three level

Study, represented by std, represents a research project that contains a set of structural variation analysis results, each study with a unique number, starting with nstd if it is from NCBI, and estd if it is from EBI

Variant regions, represented by sv, represents the region of the genome where there is a structural variation, and it also has a unique number, starting with nsv if it is from NCBI, or esv if it is from EBI.

Variant calls, represented by ssv, represents a specific structural variation event, including deletion, repetition, CNV and other types, and also has a unique number. If it comes from NCBI, it starts with nssv, and if it comes from EBI, it starts with essv.

The figure is as follows

Through Biomart, you can flexibly view and download DGVa data, as shown below

The official website also provides a download function based on study, as shown below

The data of DGva and dbvar are synchronized, but the downloaded files are in different formats. DGVa provides GCF format, while dbvar provides multiple formats such as CSV,TSV,VCF.

This is the end of this article on "what is the use of DGVa database". I hope the above content can be helpful to you, so that you can learn more knowledge. if you think the article is good, please share it out for more people to see.

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