Shulou(Shulou.com)06/02 Report--

A mother-to-be needs to be screened for Down's at 12-24 weeks of pregnancy. the accuracy of the traditional screening method is low. If the results show that the risk is high, then the mother-to-be needs to do further tests such as amniocentesis.

Today, with the development of gene sequencing technology, we can use non-invasive DNA detection, use DNA sequencing to sequence the free DNA fragments in maternal peripheral plasma, and analyze the biological information of the sequencing results, from which we can get fetal genetic information, so as to achieve accurate screening of Down's infants.

Combined with the correspondence of DNA in protein transcription and the effects of different proteins on the human body, scientists have been able to interpret a lot of information about human health and heredity from DNA. These include the probability of certain genetic defects in offspring, the probability of a disease occurring in an individual, an individual's potential allergic reaction to certain drugs or foods, and so on.

It can be said that DNA sequencing is of great significance to people's healthy life and fertility. A DNA sequencing can provide a detailed life advice and guidance for individuals or families. And this is what Wuhan Future Group Biotechnology Co., Ltd. is currently engaged in.

IT Challenge in the Field of Gene sequencing

The latest third-generation gene sequencer is not only more accurate, but also can greatly reduce the cost of gene sequencing. Now, even the average family can sequence a gene with little financial burden. Gene sequencing has become a popular means for Chinese people to pay attention to their health and improve their quality of life.

With the expansion of the personal gene sequencing market, the business of the future group has made rapid progress in just a few years. At present, the future group has developed into the largest third-generation gene sequencing company in China.

However, the booming personal gene sequencing business and a large number of scientific research work also pose a great challenge to the IT facilities of the future group.

Although the third-generation gene sequencer can quickly sequence a large number of gene fragments at the same time, because the length of human DNA sequence is up to 3 billion, if it is converted into text, then the most conservative size of this file will also reach 3GB. If the necessary redundancy factors are taken into account, the size of this file will be multiplied. The amount of data on this scale puts forward high requirements for the capacity of the storage system.

The future group already has two third-generation gene sequencers, and that number will grow to five in the future. Based on the existing business growth rate, this means that in the personal gene sequencing business alone, the daily amount of data generated is as high as 300TB to 600TB.

It can be said that the expansion rate of any local system can not catch up with the data growth on this scale. The only way out is the cloud!

Huawei promotes a new era of health with comprehensive IT technology

After repeated comparison and inspection, the future group finally chose Huawei Cloud as the main storage position in the future.

At present, the future group has worked with Huawei Cloud to open up the data transmission channel from the sequencer to Huawei cloud storage, and the genome data obtained by the sequencer can be stored directly on Huawei Cloud. With Huawei Cloud's strong resource expansion capability, large-scale gene sequencing work will no longer be limited by the storage system capacity, and the future business development of the group will also be advantageous.

At the same time, Zhu win, director of the IT Center of Wuhan Future Group Biotechnology Co., Ltd., also said: Huawei Cloud provides very comprehensive technical support services in the process of exploring cloud storage methods for gene sequencing data. The response speed of Huawei Cloud in business is also the fastest of all the cloud service providers contacted by the future group. This has established a very good relationship of cooperation and trust between the future group and Huawei.

Not only that, the Future Group is also exploring jointly with Huawei in more areas:

In a gene sequencing project called "Huaxia Wanren SV", the number of samples reached an unprecedented 10, 000. Using the existing system, each sample needs at least 360 core hours to reassemble the DNA fragment into a complete DNA sequence, which means that the entire project takes nearly 4 million nuclear hours to complete the calculation. Through the 72-hour full-load test with 100 32-core high-performance servers provided by Huawei, the whole DNA fragment reassembly takes 40, 000 core hours to complete the calculation work, and the efficiency is 100 times higher.

At the same time, the future group is also actively trying to make use of the massive memory of Huawei Kunlun minicomputer to improve the efficiency of DNA fragment reassembly computing tasks.

In the future, the future team will also try to use the heterogeneous computing services provided by Huawei Cloud to speed up the computing work of reassembling DNA fragments, and combine container technology to further improve efficiency, Zhu said. Based on Huawei Cloud, the future team will also develop a set of mobile APP for gene sequencing analysis reports, making it easier and faster for users to access gene sequencing results and get a better user experience.

Some people say that genetic engineering and biotechnology are likely to be the main directions of the fourth industrial revolution, and now we are standing at the door of this revolution.

In the end, the author believes that with the all-round development of the life science field and the comprehensive cloud of the data center, the cloud development of the life science industry is the general trend. With the arrival of cloud computing, all data and computing can be completed on the cloud, meet the enterprise data in the cloud, efficiently complete the computing needs of enterprises, reduce the importance of assets and maintenance work, and make customers focus more on their own business development.

In the field of gene sequencing, IT technology, dominated by data analysis and cloud computing, has become an important factor driving innovation and change in the industry. Rapid technological innovation and application enable doctors to provide more accurate diagnosis and treatment based on patients' genetic information, living environment and lifestyle. With strong resources, a complete and advanced product portfolio and strong service capabilities, Huawei and Huawei Cloud are paving a hybrid IT highway for biotech companies like Future Group, so that a healthier and better future can come as soon as possible.

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