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This article shows you how to annotate the information database in Gene Ontology in GOA. The content is concise and easy to understand, which will definitely brighten your eyes. I hope you can get something through the detailed introduction of this article.

GOA, whose full name is Gene Ontology Annotation, is a database of GO annotation information built by EMBL-EBI.

The database provides GO annotation information for the following three biomolecules

Proteins from UniProtKB database

RNA from RNACentral database

Protein complexes from Complex database

The annotation information of GOA database includes not only manual annotations provided by experts of the Gene Ontology committee, but also GO annotations obtained by bioinformatics software. The detailed sources are as follows

The annotation information of GOA can be browsed through QuickGO, and the FTP download function is provided on the official website, which mainly includes the following two files

1. GO comment information

The GO annotation information corresponding to proteins in the UniProtKB database is provided, as well as separate annotation files for common species.

2. Go Mapping file

The correspondence between ID and GO ID of other databases is provided as follows

The address of FTP is as follows

Ftp://ftp.ebi.ac.uk/pub/databases/GO/goa

The annotation information of GOA is browsed and retrieved through QuickGO, and the corresponding original comment information can be downloaded through FTP service.

The above is how Gene Ontology annotates the information database in GOA. Have you learned any knowledge or skills? If you want to learn more skills or enrich your knowledge reserve, you are welcome to follow the industry information channel.

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