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This article mainly introduces what unibind database is used for. The introduction in this article is very detailed and has certain reference value. Interested friends must read it!

unibind uses ChIP-eat to analyze the chip_seq data of transcription factors in ReMap database. For human transcription factors from JASPAR database, it accurately predicts transcription factor binding sites by combining the analysis results of chip_seq data with PWM models of transcription factors. The database website is as follows

https://unibind.uio.no/

The flow of data analysis is shown below

The database analyzed 231 transcription factors from 315 different tissues and cell lines, a total of 1983 chip_seq raw data, aligned with hg38 genome, identified peak regions by peak calling, and further combined with PWM, DNA shape model, TFFM, Bingding Energy model to further predict transcription factor binding sites on the basis of peak intervals.

The search box on the home page allows you to search by various keywords.

The search results are as follows

Click on each dataset to view detailed results, as shown below

On this page, you can download peak interval, bed file and fasta file of TFBS. TFBS bed format reads as follows

JASPAR database only provides motif information of transcription factors, unibind provides TFBS information on this basis, which can be regarded as a supplement to JASPAR database. TFBS information is very important for transcription factor research, and it is of great significance for studying target genes regulated by transcription factors, so this database is very practical.

The above is "unibind database what to use" all the content of this article, thank you for reading! Hope to share the content to help everyone, more relevant knowledge, welcome to pay attention to the industry information channel!

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