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2025-01-19 Update From: SLTechnology News&Howtos shulou NAV: SLTechnology News&Howtos > Internet Technology >
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This article mainly shows you "what is the fusion gene database", which is easy to understand and clear, hoping to help you solve your doubts. Let the editor lead you to study and learn the article "what is the fusion gene database?"
1. TICdb
Tumor-related fusion gene information is included in the TICdb database at
Http://www.unav.es/genetica/TICdb/
Each fusion gene in the database is supported by the literature and the corresponding pubmed number is given.
2. TCGA tumor fusion
TCGA database contains a lot of tumor-related sequencing data and analysis results. The RNA-seq data of tumors in TCGA are analyzed, filtered and sorted by the software PRADA, and a list of fusion genes with high feasibility is obtained.
Http://www.tumorfusions.org/
Because of the analysis using tumor samples, each fusion gene provides the corresponding tumor information.
3. COSMIC Fusion
In the COSMIC database, a manual list of fused genes supported by literature is provided at the following URL
Https://cancer.sanger.ac.uk/cosmic/fusion
For each fusion gene, the corresponding literature and related tissue types are given, as shown below
4. ChimerDB
ChimerDB is a comprehensive database of fusion genes, which includes fusion genes supported by literature as well as those predicted by software.
Http://203.255.191.229:8080/chimerdbv31/mindex.cdb
The database is divided into three sub-databases. CHimerKB contains fusion genes from other databases and supported by literature evidence; ChimerPub is a fusion gene predicted from articles using machine learning algorithms; ChimerSeq is a fusion gene predicted by software using TCGA RNA-seq data, as shown below
In the current research, fusion gene is usually used as a specific marker of disease. The database is downloaded free of charge and provides annotations of disease information corresponding to fusion genes.
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